cancer care center

Brain

For more information call (909) 865-9555.

RTOG 0825
Principal Investigator: Y.S. Ram Rao, M.D.
Phase III double-blind Placebo Controlled trial of Conventional Concurrent chemoradiation and Adjuvant Temozolomide Plus Bevacizumab versus Conventional concurrent Chemoradiation and adjuvant Temozolomide in patients with Newly Diagnosed Glioblastoma. **PENDING - Should be ready for enrollment in April 2010
RTOG 0614
Principal Investigator: Y.S. Ram Rao, M.D.
Whole-Brain Radiotherapy. A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brin Radiotherapy

Breast Cancer

For more information call (909) 865-9555.

RTOG 0413 / NSABP B-39
Principal Investigator: Y.S. Ram Rao, M.D.
A Randomized Phase III Study of Conventional Whole Breast Irradiation versus Partial Breast Irradiation for Women with Stage 0, I, or II Breast Cancer.

The purpose of this study is to see if partial breast irradiation is as good as or better than whole breast irradiation in keeping cancer from coming back in the breast.
CALGB 40503
Principal Investigator: Y.S. Ram Rao, M.D.
Endocrine Therapy in Combination with Anti-VEGF Therapy: A Randomized, Double-Blind, Placebo-controlled Phase III Trial of Endocrine Therapy alone or endocrine Therapy plus Bevacizumab (NSC 704865, IND 7921) for Women with Hormone Receptor-Positive Advanced Breast Cancer.
ECOG 5103
Principal Investigator: S. Chanduri, M.D.
A Double-Blind Phase III of Doxorubicin and Cyclophosphamide followed by Paclitaxel and Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer.
ECOG: PACCT-1
Principal Investigator: Y.S. Ram Rao, M.D.
Phase III Program for the assessment of clinical tests (PACCT-1) trial assigning individualized option for treatment: The TAILORx Trial.

GastroIntestional Cancers

For more information call (909) 865-9555.

NSABP-R-04
Principal Investigator: Y.S. Ram Rao, M.D.
Phase III: A clinical trial comparing preoperative radiation therapy and capecibaine with preoperative therapy and continuous intravenous infusion (CVI) of 5-FU in the treatment of patients with operable carcinoma of the rectum.

GYN Cancers

For more information call (909) 865-9555.

RTOG 0724
Principal Investigator: Y.S. Ram Rao, M.D.
A Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Follwing Radical Hysterectomy.

Lung Cancer

For more information call (909) 865-9555.

SW0G 424
Principal Investigator: Y.S. Ram Rao, M.D.
Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men.

The purpose of this study is to determine why women are more likely to be diagnosed with certain types of lung cancer than men are, and to see if factors other than smoking may put women at higher risk of lung cancer than men. We also want to understand what factors are associated with lung cancer in men and women who do not smoke.
CALGB 30610 SC
Principal Investigator: S. Rajurkar, M.D.
Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Cancer Also Receiving Cisplatin and Etoposide.

Prostate Cancer

For more information call (909) 865-9555.

RTOG 0534
Principal Investigator: Y.S. Ram Rao, M.D.
A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA After Radical Prostatectomy.

Symptom Management

For more information call (909) 865-9555.

RTOG 0517
Principal Investigator: Y.S. Ram Rao, M.D.
Randomized Phase III Trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in Osteoblastic Metastases from Lung, Breast and Prosate Cancer.

The purpose of this study is to compare the effects, good and/or bad, of a two different combinations of drugs to see which is better.
RTOG 0433
Principal Investigator: Y.S. Ram Rao, M.D.
A Phase III International Randomized Trial of Single Versus Multiple Fractions for Re-Irradiation of Painful Bone Metastases.
CALGB-70604
Principal Investigator: Y.S. Ram Rao, M.D.
A Phase III Randomized Study of Standard Dosing versus Longer Dosing Interval of Zoledronic acid in Metastatic Cancer (prostate and breast adenocarcinoma, multiple myeloma) *must have a minimum of 1 bone met.

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