Announcing our new Lung Cancer Program at PVHMC
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Dr. Rohit Trivedi and Dr. Sarika Jain
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Announcing our new Lung Cancer Program at Pomona Valley Hospital Medical Center!
Lung cancer has been the third highest incidence of cancer diagnosed at PVHMC (after breast and prostate) for the past 10 years. We formed a new multi-disciplinary specialized team in January of this year to improve early diagnosis and treatment of lung cancer,. Our program will offer assistance for patients to expedite and coordinate diagnosis. It will also streamline access to the most advanced treatment options, while offering support services and a dedicated Patient Care Coordinator. This coordinator will provide assistance to patients and their families through the entire diagnosis, treatment and recovery process. This team is being chaired by Dr. Rohit Trivedi and Dr. Sarika Jain.
The three main goals for this team are:
- Improve clinical care (resulting in better outcomes)
- Improve lung cancer awareness and prevention in the region
- Enhance the patient experience and retain more patients in our community
Lung cancer treatments have improved over the last few years, but we are still striving to improve the outcome for those diagnosed. This new team consists of primary care physicians, radiologists, cardiothoracic surgeons, pulmonologists, medical oncologists, radiation oncologists, pathologists, nursing, research and administration. They will collaborate on each case to expedite diagnosis and treatment along with the highest level of care focusing on the best outcomes.
We plan to bring you more news about the benefits and successes of this team in the near future!
The Lung Cancer Program Team
Visiting Physicist Studying Our Technology
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Front: Visiting physicist G. Mani, PhD
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Ganesh Kadirampatti Mani, Ph.D., Medical Physicist, Assistant Professor in the Department of Radiation Physics at Kidwai Memorial Institute of Oncology, Bangalore, India was awarded a Technology Transfer Fellowship from the International Union Against Cancer (UICC), partially funded by the National Cancer Institute (NCI) and other cancer organizations in Europe, North America and Australia. UICC is a non-governmental international organization dedicated solely to the global control of cancer. Dr. Mani was granted the fellowship to spend one month in the Department of Radiation Oncology at Pomona Valley Hospital Medical Center’s (PVHMC). Dr. Mani will be working with Medical Physicist Gopi Solaiappan, under the supervision of Bouchaib Rabbani, Ph.D., DABR, Professor Emeritus at the University of California, Irvine and Chief Medical Physicist in Radiation Oncology at PVHMC for over twenty years.
Dr. Mani selected to come to PVHMC to learn about our recently installed state-of-the-art technology. After the conclusion of his fellowship at PVHMC, Dr. Mani will be able to apply his experience to similar equipment/technology that his institution is currently installing. “This technology is being adapted in India and I want to know and learn all about it,” said Dr. Mani.
Physicists, working in Radiation Oncology, are scientists specializing in the unique combination of oncology medicine and radiation physics.
Their expertise is in treatment planning, treatment design and treatment implementation. They often serve as the radiation safety experts ensuring proper functioning and calibration of treatment equipment and implement quality control measures. In addition, medical physicists will often do research, teach and train other specialists in radiation physics. “We are an integral part of the patient care team, even though we don’t directly interact with patients,” explained Dr. Rabbani. The Physicist plays a major role in patient care by scientifically analyzing computerized treatment plans which results in precise delivery of treatments to the cancer target. These approaches reduce side effects to surrounding critical organs and improve outcomes and quality of life for cancer patients.
This is Dr. Mani’s first trip outside of India and while he is enjoying learning and studying about the latest technologies, he also is experiencing our hospitality. “People are very friendly here and open to teaching and learning from each other,” says Dr. Mani. The Cancer Care Center is privileged to be part of this global clinical and scientific exchange program with Medical Radiation Physicists from developing countries.
Meet our New Medical Directors
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We are excited to announce the new Medical Director Leadership team for the Oncology Program. To enhance collaboration, Dr. Y.S. Ram Rao, our Medical Director since September 2004, will be joined by Keith Kusunis, M.D., F.A.A.F.P., and Lori Lee Vanyo, M.D., F.A.C.S.
Dr. Rao completed his Residency in Radiation Oncology in 1978 at Michael Reese Medical Center in Chicago, Illinois. He moved to California in 1978 and was a Radiation Oncologist at the University of California in Irvine. He came to Pomona Valley Medical Center in 1983, serving as the Director of Radiation Oncology. "I welcome my co-director colleagues to participate in our efforts to continue to grow the Cancer Program," said Dr. Rao.
Keith Kusunis, M.D., F.A.A.F.P., completed his Residency in Family Practice in 1985 at Resurrection Hospital in Chicago, Illinois. He began his practice in 1986 in La Verne and came to Pomona Valley Hospital’s Family Health Center in November of 1998. He has served as the Chairman of the Family Practice Department and was the Chief of the Medical Staff at PVHMC in 2005. "The Cancer Program at PVHMC is already the premier site of cancer care in the Pomona Valley. I look forward to helping the continued improvement of this fine organization," said Dr. Kusunis.
Lori Lee Vanyo, M.D., F.A.C.S., completed her Residency in General Surgery in 1999 at Loma Linda University Medical Center in Loma Linda, California. Dr. Vanyo joined the Medical Staff at PVHMC in 1999. She has served on many medical staff committees including Cancer Committee, where she was our American College of Surgeons liaison from 2000 – 2005.
She is currently the Chief of Surgery at PVHMC. Dr. Vanyo said "I look forward to working as a team to help deliver state-of-the-art cancer care/treatment in a loving and supportive environment."
These doctors will work in collaboration with Shellee Reese, RN, BSN, MHA, OCN, and Administrative Director to support the oncology service line development, refinement and growth. Their leadership will have primary responsibility for all clinically related activities within the Cancer Center, supporting inpatient services, supportive care programs, and services. Also, they will contribute to administrative functions such as Tumor Registry, clinical research, outcomes reporting, etc., including quality control and problem-solving for clinical concerns.
Additionally, they will monitor financial performance and intervene to assure the attainment of utilization management objectives. They also serve as primary communicators to physicians who are current or potential users of oncology services.
New CT Scanner Installed!
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Our new GE Lightspeed 14RT dedicated treatment planning CT scanner began clinical use in Radiation Oncology in February. It allows patients to come to the Center to get this necessary scan which is part of the treatment planning process, making it quicker and more convenient than having to go to the Hospital to have this done.
This wide bore CT unit has a larger diameter opening to allow patients more room for improved positioning over what was available with the narrow bore CT scanners at the hospital. Special computer controlled lasers are also part of the new GE CT Simulation Scanner. The lasers are used to more accurately determine the exact center of where the radiation needs to be delivered and are directed by the treatment planning systems. While the new GE CT Simulation Scanner was being installed, GE provided a mobile CT scanner in a truck that we used to do this CT treatment planning.
Once again, we are always striving to make the cancer experience easier and more convenient for our patients while providing state of the art technology and outstanding radiation medicine.
New PET/CT Scanner is Here!
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Positron emission tomography (PET) combined with computed tomography (CT) represent a major advance in the diagnosis, treatment and management of patients with cancer. While the Department of Radiology here at Pomona Valley Hospital Medical Center (PVHMC) has been providing PET imaging since 2001, our installation of a dedicated PET/CT scanner in August 2007 has substantially improved the quality and value of our imaging services to patients with cancer.
To understand why PET is so valuable in cancer care today, we’ll need first to review a little basic biology. Many living cells use glucose and other fuels as their source of energy. Cancer cells, however, have a more "primitive" metabolic system, and use much more glucose, and use it less efficiently, than normal cells. Fluorodeoxyglucose (FDG) is an analog of glucose, and this molecule gets trapped preferentially inside cells with relatively immature metabolic pathways, specifically in cancer cells. Radioactive fluorine 18 is attached to the fluorodeoxyglucose, to make 18-FDG; it is this radiopharmaceutical which is injected into patients to produce their PET images. Because the 18-FDG localizes primarily to cancer cells, our imaging system, the PET scanner can reconstruct in three dimensions the location of concentrations of 18-FDG, and therefore, demonstrate the location of cells with a malignant type of metabolism.
FDG PET is one of the first examples of molecular imaging. However, to enhance the relatively low resolution of these PET imaging, we need to localize potential sites of cancer with high anatomic accuracy as well.
This is where CT comes in. CT has a resolution on the order of millimeters, and when combined with PET localizing areas of cancer cell growth, we can get an excellent image of the patient’s extent, location and activity of disease.
In patients with active tumors, the PET scan shows areas of viable cancer cells as "bright" spots, accumulating FDG. The CT scan assists the radiologist and surgeons to define the exact anatomic location of the abnormal cancer cells. Because the PET scan and the CT scan are performed on each patient at essentially the same time, the correspondence of the PET and CT abnormality is very reliable.
Our PET/CT imager at Pomona Valley Hospital is the Siemens biograph 40, and it’s really two state-of-the-art imaging devices in a single machine. The PET scanner uses the most modern, high response, high sensitivity detector crystals to image the high energy photons liberated by the fluorine-18 FDG. The CT scanner has 40 detector rows, and thus acquires 40 images in each pass of 370 msec; it can perform routine CT scans and CT of the heart as well. At a cost of over $2.1 million, the biograph 40 is a major technology investment by PVHMC in advanced health care for the Pomona community.
PET/CT has been shown useful in a wide variety of common cancers, and is seen as indispensable in the management of some of these dread diseases.
In lung cancer, prior to surgery, it’s important to know if there has been spread to lymph nodes or beyond the chest. PET/CT can demonstrate that there may be value to surgery if no spread is identified, or can avert major surgery if there has been extensive local or distant spread.
In colon, esophageal and pancreatic cancer, PET/CT is useful in evaluating patients with suspected recurrence. Often blood tests may show elevation in tumor markers, suggesting spread of cancer, though a routine CT scan may not identify the location of spread. PET/CT allows oncologists to confidently identify an occult location of spread, or to confirm that there is no spread.
Similarly, in breast cancer, patients with known spread of cancer to distant sites may be effectively and aggressively treated with chemotherapy, surgery or radiotherapy. PET/CT is a reliable and accurate way to assess response of the disease spread to treatment. Lymphoma is another disease which oncologists follow closely during treatment with PET/CT scans.
There will be about 1.4 million new cases of cancer diagnosed in 2007, and about 560,000 deaths. Each of us has a one in three risk of succumbing to this disease. The tumors most effectively imaged with PET/CT are among the most common: lung, breast, colorectal, uterus, ovary, thyroid, lymphoma, melanoma, and pancreas. With PET/CT radiologists and oncologists have new and powerful tools to diagnose and manage this group of diseases.
by Johnson B. Lightfoote, M.D., Medical Director, Department of Radiology
Trilogy - Making a Difference!
Radiation therapy, using our new state-of-the art machine, was made available to our patients in April, 2007. “This system makes it possible for us to treat patients with the most advanced radiation therapy techniques, using the most clinically efficient processes in the world,” says Ram Rao, M.D., Radiation Oncologist.
Angela May was diagnosed with breast cancer in October 2006 and started her radiation therapy in June 2007. “Getting radiation wasn’t like I expected at all. I thought I would see laser beams but instead it was just this big machine moving around me. I was more annoyed that I would have to come every week day for 33 treatments and I thought it would be more time consuming then it actually is. The wonderful therapists’ are great to me and the treatment is so fast – I’m in and out in just a few minutes! I have had no side-effects and I don’t mind at all coming here every day,” explained Angela.
Marcia Van’t Land was diagnosed with breast cancer in April of this year. Radiation followed her lumpectomy. “I like how this machine is saving my lung... my cancer is very close to the chest wall and the beams are contoured to avoid hitting my lung. I do have some fatigue, but the Doctor explained that is pretty normal. I’ve also found the breast cancer support group very helpful and would recommend this Center to anyone,” Marcia shared.
Raymond Edwards was diagnosed with pancreatic cancer in December 2006. Radiation followed surgery and chemotherapy and he has more treatment planned after radiation is completed. “I had no idea what to expect, but I have had no side effects, other than fatigue. I like the fact that the Center is so close to my home (Chino). The easy parking, nice clean place with nice people make going their comfortable. This new big machine whirls around me and the treatment is over in 15 minutes,” said Raymond.
“The extraordinary power and flexibility of the Trilogy system assure us that we can design a treatment plan that gives our patients the best and most appropriate treatment possible,” explained Dr. Rao. “By combining the most powerful radiation therapy treatment machine with high quality imaging, tracking and monitoring devices, Trilogy allows us to deliver the most accurate treatments possible in the shortest amount of time. This translates to better outcomes along with greater patient comfort, since patients spend less time on the treatment table. We are extremely gratified to be able to offer this system to our patients.”
The Newest and Most Advanced Technology is Here!
We are proud to announce the arrival of the newest and most advanced technology available in the treatment of cancer with radiation. The all-new $2,500,000 Varian Trilogy linear accelerator has features unmatched by other models or manufacturers. Trilogy comes with a 120 multileaf collimator (MLC), Electronic Portal Imaging (EPID), On Board Imaging System (OBI), Respiratory Gating and extremely tight mechanical tolerances. The Trilogy linear accelerator is the most technically advanced linear accelerator in the world.
With the MLC, radiation fields can be modified and adjusted during the treatment to fit the patient position. These fine adjustments allow us to shield adjacent normal tissues while giving the highest feasible dose to the tumor. Further, the MLC is used to deliver Intensity Modulated Radiation Treatments (IMRT) by allowing each “leaf” to move independently of the other “leaves.” This way, we can pinpoint radiation to areas as small as 5 mm by 5 mm. This leads to a customized plan for each tumor size and location in each patient. With the additional positioning devices and techniques, IMRT holds a great hope for controlling the most challenging tumor sites, such as head and neck cancers, spinal cord tumors, brain tumors, prostate cancer, and more.
The ability to direct radiation is limited by how well we can position the patient. The Trilogy comes with an EPID that allows us to monitor the patient radio-graphically during treatment. Images are generated and monitored for changes and corrections during the treatment.
Another important advancement that Trilogy brings to The Robert and Beverly Lewis Family Cancer Care Center is the ability to generate CT like images with the patient in the treatment position. This improves the pinpointing of the tumor location before treatments are delivered. We can look inside the body with greater accuracy and clinically respond to tumor changes.
While patients breathe, the tumor may move with the breathing rhythm. Trilogy comes with a system to allow us to monitor the breathing cycle and deliver the dose only when the tumor is at predetermined positions. The advantage to this is that we are able to use tighter margins around tumors, which results in less treatment of normal tissue and the less unwanted side effects.
With its stringent and tight mechanical tolerance, Trilogy allow us to be more precise in our treatment than ever before.
Our patients will benefit from the new Trilogy technology by having better control of the tumors even when they are located in difficult areas to treat - More advanced technology means greater tumor control and greater hope of cure.
Buchaib Rabbani, Ph.D., Radiaton Physicist
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